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A Collection of Very Valuable and Scarce Pieces Relating to the last Plague in the Year 1665 (London, 1721) is a book which includes a collection of documents relating to the plague in London. This book was used to help prevent future diseases from being as destructive as the plague was in London during the late-sixteenth and seventeenth centuries. The first chapter includes orders made by the Mayor Lord of London that were meant to help prevent the spread of disease. This section includes instructions on when to report illness, how to handle sick patients and their belongings, as well as other orders the Mayor believed would be effective in containing the spread of disease. The second section of the book includes personal accounts from Dr. Hodges on different symptoms as well as his experiences with the disease. The third section presents remedies and possible cures for the plague. The book also includes the weekly bills of mortality for three different bouts of plague that hit London. The final part of this book includes an account of the Plague of 1665 in Italy. This book is a compilation of different documents on how to handle disease.